Susan K. Lutgendorf

Name:	Susan Lutgendorf	(Click to see whole picture)
Address:	E 228 Seashore Department of Psychology University of Iowa Iowa City, IA 52242-1407
Phone:	(319) 335 - 2432
E-mail:	susan-lutgendorf@uiowa.edu
Courses Taught:	31: 013 Introduction to Clinical Psychology
31: 168 Psychotherapies
31: 266 Psychological Therapies
31: 370 Health Psychology Seminar: Introduction to Psychoneuroimmunology
Interests:	Psychoneuroimmunology Biobehavioral mechanisms in Cancer, Aging and Inflammatory Diseases Effects of Behavioral Medicine Interventions on Immunity: Cognitive Behavioral Stress Management, Medical Hypnosis, Relaxation, Disclosure Adjustment to Chronic Illness: Cancer, HIV, Inflammatory Diseases Alternative Medicine
NIH Networks:	Dr. Lutgendorf is a core member of the National Cancer Institute Network on Biobehavioral Pathways in Cancer. The mission of this network is to accelerate the translation and communication of biobehavioral discoveries to advance clinical cancer care. The Network fosters research excellence through the integration and dissemination of relevant scientific discoveries and the identification, support, and communication of new research directions in the field of biobehavioral pathways in cancer. Dr. Lutgendorf is also a member of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Multidisciplinary Approach to Pelvic Pain (MAPP) network.
Other:	Click here to view Dr. Lutgendorf's Professional Summary.
Research:	Lutgendorf Laboratory
Funding:	Current and Recent Funding
Photo Album	Click here to view photos

Name:

Susan Lutgendorf

(Click to see whole picture)

Address:

E 228 Seashore
Department of Psychology
University of Iowa Iowa City, IA 52242-1407

Phone:

(319) 335 - 2432

E-mail:

susan-lutgendorf@uiowa.edu

Courses Taught:

31: 013 Introduction to Clinical Psychology

31: 168 Psychotherapies

31: 266 Psychological Therapies

31: 370 Health Psychology Seminar: Introduction to Psychoneuroimmunology

Interests:

Psychoneuroimmunology
Biobehavioral mechanisms in Cancer, Aging and Inflammatory Diseases
Effects of Behavioral Medicine Interventions on Immunity: Cognitive Behavioral Stress Management, Medical Hypnosis, Relaxation, Disclosure
Adjustment to Chronic Illness: Cancer, HIV, Inflammatory Diseases
Alternative Medicine

NIH Networks:

Dr. Lutgendorf is a core member of the National Cancer Institute Network on Biobehavioral Pathways in Cancer. The mission of this network is to accelerate the translation and communication of biobehavioral discoveries to advance clinical cancer care. The Network fosters research excellence through the integration and dissemination of relevant scientific discoveries and the identification, support, and communication of new research directions in the field of biobehavioral pathways in cancer.

Dr. Lutgendorf is also a member of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Multidisciplinary Approach to Pelvic Pain (MAPP) network.

Other:

Click here to view Dr. Lutgendorf's Professional Summary.

Research:

Lutgendorf Laboratory

Funding:

Current and Recent Funding

Photo Album

Click here to view photos

Selected Recent Publications
1. Antoni, M.H., Lutgendorf, S.K., Blomberg, B., Carver, C.S., Lechner, S., Diaz, A., Stagl, J., Arevalo, J.M.G., Cole, S. W. (in press). Cognitive-behavioral stress management reverses anxiety-related leukocyte transcriptional dynamics. Biological Psychiatry.
2. Lamkin, D. M., Lutgendorf, S.K., Lubaroff, D.M., Sood, A.K., Beltz, T.G., Johnson, A.K. (2011). Cancer induces inflammation and depressive-like behavior in the mouse: Modulation by social housing. Brain, Behavior, and Immunity. 25, 555-64. PubMed Central PMCID: PMC3039064
3. Moreno-Smith M, Lu C, Shahzad MM, Pena GN, Allen JK, Stone RL, Mangala LS, Han HD, Kim HS, Farley D, Berestein GL, Cole SW, Lutgendorf SK, Sood AK. (2011). Dopamine Blocks Stress-Mediated Ovarian Carcinoma Growth, Clin Cancer Res. 17, 3649-59.
4. Lutgendorf, S.K. , DeGeest, K., Dahmoush, L., Farley, D., Penedo, F., Bender, D., Goodheart, M., Buekers, T.E., Mendez, L., Krueger, G., Clevenger, L., Lubaroff, D.M., Sood, A.K., Cole, S.W. (2010) Social Isolation is associated with Elevated Tumor Norepinephrine in Ovarian Carcinoma Patients. Brain Behavior and Immunity, 25, 250-5. NIHMS251278
5. Lutgendorf, S.K., Mullen,E., Russell, D., DeGeest. K., Jacobson, G.M., Hart, L., Anderson, B., Bender, D., Buekers, T., Goodheart, M., Antoni, M., Sood, A., Lubaroff, D. (2010) Preservation of immune function in cervical cancer patients during chemoradiation treatment using a novel integrative approach. Brain, Behavior and Immunity. 24, 1231-40. doi: 10.1016/j.bbi.2010.06.014 NIHMSID 219317.
6. Weinrib, A., Sephton, S.E., DeGeest, K., Penedo, F., Bender, D., Zimmerman, B., Kirschbaum, C. , Sood, A., Lubaroff, D.M., Lutgendorf, S.K. (2010). Diurnal Cortisol Dysregulation: Links with Depression and Functional Disability in Women with Ovarian Cancer. Cancer. 116, 4410-9. PMID 20564155. NIHMS286552.
7. Sood, A.K., Armaiz-Pena, G.N., Halder, J., Nick, A.M., Stone, R.L., Hu, W., Carroll, A.R., Spannuth, W.A., Deavers, M.T., Allen, J.K., Han, L.Y., Kamat, A.A., Shahzad, M.M.K, McIntyre, B.W., Diaz-Montero, C.M., Jennings, N.B., Lin, Y.G., Merritt, W.M., DeGeest,K., Vivas-Mejia, P.E., Lopez-Berestein, G., Schaller, M.D., Cole, S.W., Lutgendorf, S.K. (2010). Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. Journal of Clinical Investigation.120, 1515-23. PMCID: PMC2860925.
8. Cole, S.W., Arevalo, J.M., Takahashi, R., Sloan, E.K., Lutgendorf, S.K., Sood, A.K., Sheridan, J.F., Seeman, T.E. (2010). Computational identification of gene-social environment interaction at the human IL6 locus. Proceedings of the National Academy of Sciences, USA. 107, 5681-5686 PMCID: PMC2851818
9. Costanzo, E. S., Lutgendorf, S. K., & Roman, S. L. (2010). Common- sense beliefs about breast cancer and health practices among women completing treatment for breast cancer. Psycho-Oncology. 20, 53-61. NIHMS192078
10. Lang, E.V., Berbaum, K., Lutgendorf, S. (2009). Large-core breast biopsy: Abnormal salivary cortisol profiles associated with uncertainty of diagnosis. Radiology. 250, 631-637.
11. Lutgendorf, S.K., DeGeest, K., Sung, C.Y., Arevalo, J.M.G., Penedo, F., Lucci, J.A. III, Goodheart, M., Lubaroff, D., Farley, D.M., Sood, A.K., Cole, S.W. (2009). Depression, Social Support, and Beta-Adrenergic Transcription Control in Human Ovarian Cancer Brain, Behavior, and Immunity. (PMCID #18550328) 23, 176-183, June 10 epub ahead of print. PMCID: PMC2677379.
12. Lutgendorf, S.K., Lamkin, D.M., Jennings, N.B., Arevalo, J.M.G., Penedo, F., DeGeest, K., Langley, R.R., Lucci, J.A. III, Cole, S.W., Lubaroff, D.M., Sood, A.K. (2008). Biobehavioral Influences on Matrix Metalloproteinase Expression in Ovarian Carcinoma, Clinical Cancer Research, 14, 6839-46. PMCID: PMC2716059 NIHMS 114621
13. Lutgendorf, S.K., Weinrib, A.Z., Penedo, F., Russell, D., DeGeest, K., Costanzo, E.S., Henderson, P.J., Sephton, S.E., Rohleder, N., Lucci, J.A. III, Cole, S., Sood, A.K., Lubaroff, D. (2008). Interleukin-6, Cortisol, and Depressive Symptoms in Ovarian Cancer Patients. Journal of Clinical Oncology, 26, 4820-7, Sep 8 epub ahead of print. PMCID: PMC2653140
Review Papers
1. Lutgendorf, S. & Sood, A. (in press) Biobehavioral Factors and Cancer Progression: Physiological Pathways and Mechanisms. Invited review, Psychosomatic Medicine.
2. Costanzo, E.S., Sood, A.K., Lutgendorf, S.K. (2011). Biobehavioral Influences on Cancer Progression. Allergy and Immunology Clinics of North America, 31, 109-132. Central PMCID: PMC3011980
3. Lutgendorf, S.K., Antoni, M., Sood, A. (2010). Host Factors and Cancer Progression: Biobehavioral Signaling pathways and Interventions. Journal of Clinical Oncology, 28, 4094-9. PMCID: PMC2940426
4. Moreno-Smith M., Lutgendorf S.K., Sood A.K. (2010). Impact of stress on cancer metastasis. Future Oncology 6(12):1863-1881. PMC3037818
5. Lutgendorf, S. (2009) Positive Affect and Radiation-Induced Inflammation: Insights into Inflammatory Regulation? Brain, Behavior, and Immunity. 23,1066-7. Epub 2009 Sep 3. NIHMS 151056
6. Lutgendorf, S. and Laudenslager, M. (2009). Stress and Dysregulation of Inflammatory Control in Cancer Caregivers. Journal of Clinical Oncology 27, 2894-5.

Selected Recent Publications

1. Antoni, M.H., Lutgendorf, S.K., Blomberg, B., Carver, C.S., Lechner, S., Diaz, A., Stagl, J., Arevalo, J.M.G., Cole, S. W. (in press). Cognitive-behavioral stress management reverses anxiety-related leukocyte transcriptional dynamics. Biological Psychiatry.

2. Lamkin, D. M., Lutgendorf, S.K., Lubaroff, D.M., Sood, A.K., Beltz, T.G., Johnson, A.K. (2011). Cancer induces inflammation and depressive-like behavior in the mouse: Modulation by social housing. Brain, Behavior, and Immunity. 25, 555-64. PubMed Central PMCID: PMC3039064

3. Moreno-Smith M, Lu C, Shahzad MM, Pena GN, Allen JK, Stone RL, Mangala LS, Han HD, Kim HS, Farley D, Berestein GL, Cole SW, Lutgendorf SK, Sood AK. (2011). Dopamine Blocks Stress-Mediated Ovarian Carcinoma Growth, Clin Cancer Res. 17, 3649-59.

4. Lutgendorf, S.K. , DeGeest, K., Dahmoush, L., Farley, D., Penedo, F., Bender, D., Goodheart, M., Buekers, T.E., Mendez, L., Krueger, G., Clevenger, L., Lubaroff, D.M., Sood, A.K., Cole, S.W. (2010) Social Isolation is associated with Elevated Tumor Norepinephrine in Ovarian Carcinoma Patients. Brain Behavior and Immunity, 25, 250-5. NIHMS251278

5. Lutgendorf, S.K., Mullen,E., Russell, D., DeGeest. K., Jacobson, G.M., Hart, L., Anderson, B., Bender, D., Buekers, T., Goodheart, M., Antoni, M., Sood, A., Lubaroff, D. (2010) Preservation of immune function in cervical cancer patients during chemoradiation treatment using a novel integrative approach. Brain, Behavior and Immunity. 24, 1231-40. doi: 10.1016/j.bbi.2010.06.014 NIHMSID 219317.

6. Weinrib, A., Sephton, S.E., DeGeest, K., Penedo, F., Bender, D., Zimmerman, B., Kirschbaum, C. , Sood, A., Lubaroff, D.M., Lutgendorf, S.K. (2010). Diurnal Cortisol Dysregulation: Links with Depression and Functional Disability in Women with Ovarian Cancer. Cancer. 116, 4410-9. PMID 20564155. NIHMS286552.

7. Sood, A.K., Armaiz-Pena, G.N., Halder, J., Nick, A.M., Stone, R.L., Hu, W., Carroll, A.R., Spannuth, W.A., Deavers, M.T., Allen, J.K., Han, L.Y., Kamat, A.A., Shahzad, M.M.K, McIntyre, B.W., Diaz-Montero, C.M., Jennings, N.B., Lin, Y.G., Merritt, W.M., DeGeest,K., Vivas-Mejia, P.E., Lopez-Berestein, G., Schaller, M.D., Cole, S.W., Lutgendorf, S.K. (2010). Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. Journal of Clinical Investigation.120, 1515-23. PMCID: PMC2860925.

8. Cole, S.W., Arevalo, J.M., Takahashi, R., Sloan, E.K., Lutgendorf, S.K., Sood, A.K., Sheridan, J.F., Seeman, T.E. (2010). Computational identification of gene-social environment interaction at the human IL6 locus. Proceedings of the National Academy of Sciences, USA. 107, 5681-5686 PMCID: PMC2851818

9. Costanzo, E. S., Lutgendorf, S. K., & Roman, S. L. (2010). Common- sense beliefs about breast cancer and health practices among women completing treatment for breast cancer. Psycho-Oncology. 20, 53-61. NIHMS192078

10. Lang, E.V., Berbaum, K., Lutgendorf, S. (2009). Large-core breast biopsy: Abnormal salivary cortisol profiles associated with uncertainty of diagnosis. Radiology. 250, 631-637.

11. Lutgendorf, S.K., DeGeest, K., Sung, C.Y., Arevalo, J.M.G., Penedo, F., Lucci, J.A. III, Goodheart, M., Lubaroff, D., Farley, D.M., Sood, A.K., Cole, S.W. (2009). Depression, Social Support, and Beta-Adrenergic Transcription Control in Human Ovarian Cancer Brain, Behavior, and Immunity. (PMCID #18550328) 23, 176-183, June 10 epub ahead of print. PMCID: PMC2677379.

12. Lutgendorf, S.K., Lamkin, D.M., Jennings, N.B., Arevalo, J.M.G., Penedo, F., DeGeest, K., Langley, R.R., Lucci, J.A. III, Cole, S.W., Lubaroff, D.M., Sood, A.K. (2008). Biobehavioral Influences on Matrix Metalloproteinase Expression in Ovarian Carcinoma, Clinical Cancer Research, 14, 6839-46. PMCID: PMC2716059 NIHMS 114621

13. Lutgendorf, S.K., Weinrib, A.Z., Penedo, F., Russell, D., DeGeest, K., Costanzo, E.S., Henderson, P.J., Sephton, S.E., Rohleder, N., Lucci, J.A. III, Cole, S., Sood, A.K., Lubaroff, D. (2008). Interleukin-6, Cortisol, and Depressive Symptoms in Ovarian Cancer Patients. Journal of Clinical Oncology, 26, 4820-7, Sep 8 epub ahead of print. PMCID: PMC2653140

Review Papers

1. Lutgendorf, S. & Sood, A. (in press) Biobehavioral Factors and Cancer Progression: Physiological Pathways and Mechanisms. Invited review, Psychosomatic Medicine.

2. Costanzo, E.S., Sood, A.K., Lutgendorf, S.K. (2011). Biobehavioral Influences on Cancer Progression. Allergy and Immunology Clinics of North America, 31, 109-132. Central PMCID: PMC3011980

3. Lutgendorf, S.K., Antoni, M., Sood, A. (2010). Host Factors and Cancer Progression: Biobehavioral Signaling pathways and Interventions. Journal of Clinical Oncology, 28, 4094-9. PMCID: PMC2940426

4. Moreno-Smith M., Lutgendorf S.K., Sood A.K. (2010). Impact of stress on cancer metastasis. Future Oncology 6(12):1863-1881. PMC3037818

5. Lutgendorf, S. (2009) Positive Affect and Radiation-Induced Inflammation: Insights into Inflammatory Regulation? Brain, Behavior, and Immunity. 23,1066-7. Epub 2009 Sep 3. NIHMS 151056

6. Lutgendorf, S. and Laudenslager, M. (2009). Stress and Dysregulation of Inflammatory Control in Cancer Caregivers. Journal of Clinical Oncology 27, 2894-5.