John Freeman

Publications

(Since 2000)

Professor

Stanton, M.E. & Freeman, J.H., Jr. (2000). Developmental studies of eyeblink conditioning in a rat model. In D.S. Woodruff-Pak and J.E. Steinmetz (Eds.) Eyeblink Classical Conditioning: Animal. Amsterdam: Kluwer.

Freeman, J.H., Jr. & Nicholson, D.A. (2000). Developmental changes in eye-blink conditioning and neuronal activity in the cerebellar interpositus nucleus. Journal of Neuroscience, 20, 813-819. PDF

Nicholson, D.A. & Freeman, J.H., Jr. (2000). Lesions of the perirhinal cortex impair sensory preconditioning in rats. Behavioural Brain Research, 112, 69-75. PDF

Nicholson, D.A. & Freeman, J.H., Jr. (2000). Developmental changes in eye-blink conditioning and neuronal activity in the inferior olive. Journal of Neuroscience, 20, 8218-8226. PDF

Freeman, J.H., Jr. & Nicholson, D.A. (2001). Ontogenetic changes in the neural mechanisms of eyeblink conditioning. Integrative Physiological and Behavioral Science, 36, 15-35.

Smith, D.M., Monteverde, J., Schwartz, E., Freeman, J.H., Jr., & Gabriel, M. (2001). Lesions in the central nucleus of the amygdala: effects on discriminative avoidance learning, discriminative approach learning and cingulothalamic training-induced neuronal activity. Neurobiology of Learning & Memory, 76, 403-425.

Nicholson, D.A. & Freeman, J.H., Jr. (2002). Neuronal correlates of conditioned inhibition of the eyeblink response in the anterior interpositus nucleus. Behavioral Neuroscience, 116, 22-36. PDF

Nicholson, D.A. & Freeman, J.H., Jr. (2002). Medial dorsal thalamic lesions impair latent inhibition and blocking of the conditioned eyeblink response in rats. Behavioral Neuroscience, 116, 276-285. PDF

Wemmie, J.A., Chen, J., Askwith, C.C., Hruska-Hageman, A.M., Price, M.P., Nolan, B.C., Yoder, P.G., Lamani, E., Hoshi, T., Freeman, J.H., Jr., & Welsh, M.J. (2002). The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory. Neuron, 34, 463-477.

Smith, D.M., Freeman, J.H., Jr., Nicholson, D.A., & Gabriel, M. (2002). Limbic thalamic lesions, appetitively motivated discrimination learning, and training-induced neuronal activity in rabbits. Journal of Neuroscience, 22, 8212-8221.

Kleim, J.A.*, Freeman, J.H., Jr.*, Bruneau, R., Nolan, B.C., Cooper, N.R., Zook, A., & Walters, D. (2002). Synapse formation is associated with memory storage in the cerebellum. Proceedings of the National Academy of Sciences (USA), 99, 13228-13231. PDF

Nolan, B.C., Nicholson, D.A., & Freeman, J.H., Jr. (2002). Blockade of GABA_A receptors in the interpositus nucleus modulates expression of conditioned excitation but not conditioned inhibition of the eyeblink response. Integrative Physiological & Behavioral Science, 37, 293-310. PDF

Freeman, J.H., Jr., Nicholson, D.A., Muckler, A., Rabinak, C., & DiPietro, N. (2003). Ontogeny of eyeblink conditioned response timing in rats. Behavioral Neuroscience, 117, 283-291. PDF

Nicholson, D.A, & Freeman, J.H., Jr. (2003). Addition of inhibition in the olivocerebellar system and the ontogeny of a motor memory. Nature Neuroscience, 6, 532-537. PDF

Wemmie, J.A., Askwith, C.C., Lamani, E., Cassell, M.D., Freeman, J.H., Jr., & Welsh, M.J. (2003). Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. Journal of Neuroscience, 23, 5496-5502.

Nicholson, D.A., Sweet, J.A., & Freeman, J.H., Jr. (2003). Long-term retention of the classically conditioned eyeblink response in rats. Behavioral Neuroscience, 117, 871-875. PDF

Nicholson, D.A., & Freeman, J.H., Jr. (2003). Developmental changes in evoked Purkinje cell complex spike responses. Journal of Neurophysiology, 90, 2349-2357. PDF

Freeman, J.H., Jr, & Muckler, A.S. (2003). Developmental changes in eyeblink conditioning and neuronal activity in the pontine nuclei. Learning & Memory, 10, 337-345. PDF

Nicholson, D.A., & Freeman, J.H., Jr. (2004). Developmental changes in eyeblink conditioning and simple spike activity in the cerebellar cortex. Developmental Psychobiology, 44, 45-57. PDF

Freeman, J.H., Jr., & Nicholson, D.A. (2004). Developmental changes in the neural mechanisms of eyeblink conditioning. Behavioral and Cognitive Neuroscience Reviews, 3, 3-13. PDF

Nicholson, D.A., & Freeman, J.H., Jr. (2004). Selective developmental increase in the climbing fiber input to the cerebellar interpositus nucleus in rats. Behavioral Neuroscience, 118, 1111-1116. PDF

Lim, R., Zaheer, A., Khosravi, H., Freeman, J.H., Jr., Halverson, H.E., Wemmie, J.A., &Yang, B. (2004). Impaired motor performance and learning in glia maturation factor-knockout mice. Brain Research, 1024, 225-232.

Freeman, J.H., Jr., & Rabinak, C.A. (2004). Eyeblink conditioning in rats using pontine stimulation as a conditioned stimulus. Integrative Physiological & Behavioral Science, 39, 180-191. PDF

Nolan, B.C., & Freeman, J.H., Jr. (2005). Purkinje cell loss by OX7-saporin impairs excitatory and inhibitory eyeblink conditioning. Behavioral Neuroscience, 119, 190-201. PDF

Freeman, J.H., Jr., Halverson, H.E., & Poremba, A. (2005). Differential effects of cerebellar inactivation on eyeblink conditioned excitation and inhibition. Journal of Neuroscience, 25, 889-895. PDF

Freeman, J.H., Jr., Rabinak, C.A., & Campolattaro, M. (2005). Pontine stimulation overcomes developmental limitations in the neural mechanisms of eyeblink conditioning. Learning & Memory, 12, 255-259. PDF

Campolattaro, M.M., & Freeman, J.H. (2006). Perirhinal cortex lesions impair feature-negative discrimination. Neurobiology of Learning and Memory, 86, 205-213.

Halverson, H.E., & Freeman, J.H. (2006). Medial auditory thalamic nuclei are necessary for eyeblink conditioning. Behavioral Neuroscience, 120, 880-887.

Campolattaro, M.M., & Freeman, J.H. (2006). Perirhinal cortex lesions impair feature-positive discrimination. Behavioral Neuroscience, 120, 970-975.

Nolan, B.C., & Freeman, J.H. (2006). Purkinje cell loss by OX7-saporin impairs acquisition and extinction of eyeblink conditioning. Learning & Memory, 13, 359-365.

Plakke, B., Freeman, J.H., & Poremba, A. (2007). Metabolic mapping of the rat cerebellum during delay and trace eyeblink conditioning. Neurobiology of Learning and Memory, 88, 11-18.

Campolattaro, M.M., Halverson, H.E., & Freeman, J.H. (2007). Medial auditory thalamic stimulation as a conditioned stimulus for eyeblink conditioning in rats. Learning & Memory, 14, 152-159.

Freeman, J.H., Halverson, H.E., & Hubbard, E.M. (2007). Inferior colliculus lesions impair eyeblink conditioning in rats. Learning & Memory, 14, 842-846.

Hunt, P.S., Fanselow, M.S., Richardson, R., Mauk, M.D., Freeman, J.H., and Stanton, M.E. (2007). Synapses, Circuits and the Ontogeny of Learning. Developmental Psychobiology, 49, 649-663.

Campolattaro, M.M., Schnitker, K.M., & Freeman, J.H. (2008). Changes in inhibition during differential eyeblink conditioning with increased training. Learning & Behavior, 36, 158-164.

Campolattaro, M.M., & Freeman, J.H. (2008). Eyeblink conditioning in 12-day-old-rats using pontine stimulation as the conditioned stimulus. Proceedings of the National Academy of Sciences (USA), in press.